What makes Bionano's approach to genomics different?

Bionano’s Saphyr system uses a scanning electron microscope to detect structural variations in DNA at a resolution of 6 nm. This structural information is used to produce a high-resolution, genome-wide map of structural variation. The differences in the physical structure of the DNA can then be used to identify and isolate disease-causing genetic variants.

The Bionano genome mapping approach is different from other genomics approaches in a few ways. First, traditional genomics methods sequence the entire genome and then look for variants. This can be a time-consuming process, and can miss structural variants that are not present in the sequencing data. Bionano’s approach does not require sequencing and can detect structural variants that are not found in the sequence data.

Second, the Bionano approach uses information on the physical structure of the DNA to identify variants. This approach is more accurate than other methods and can identify variants that are not found by other methods.

Third, the Bionano approach is faster and less expensive than other methods. Sequencing the entire genome can be expensive and time-consuming. The Bionano approach does not require sequencing and is faster and less expensive.

Fourth, the Bionano approach can be used to detect structural variants in any species. Other methods can only detect variants in a few species. The Bionano approach can be used to detect variants in any species.

Conclusion

Bionano's approach to genomics is based on its Saphyr system, which uses a laser to create maps of single molecules of DNA. This approach is different from other methods because it is extremely precise and can map long pieces of DNA.